What is MIDI? It stands for Musical Instrument Digital Interface. Officially born in 1983, it is a protocol that does not contain audio. Rather, it works by telling sound generating devices (synths, samplers, etc.) how to generate sounds. Highly flexible, MIDI does not take up a lot of space on your hard drive and makes changing and editing performances and sounds easy. Although is can be frustrating for new users at first, MIDI is your friend. Be patient with MIDI.